CONSORT-DEFINE EXPLANATION AND ELABORATION: RECOMMENDATIONS FOR ENHANCING REPORTING QUALITY AND IMPACT OF EARLY PHASE DOSE-FINDING CLINICAL TRIALSRESEARCH IN CONTEXT

Summary: Early phase dose-finding (EPDF) trials are key in the development of novel therapies, with their findings directly informing subsequent clinical development phases and providing valuable insights for reverse translation.Comprehensive and transparent reporting of these studies is critical mars landing kale for their accurate and critical in

Extreme weather events are occurrences of unusually severe weather or climate conditions that can devastate local communities, agriculture and natural ecosystems.Due to climate change, these extreme events are becoming increasingly more likely, lasting longer, and more severe in impact.In this paper, we illustrate the potential effects of concurren

Ho-Shan Niu,1 I-Min Liu,2 Chiang-Shan Niu,1 Po-Ming Ku,3,4 Chao-Tien Hsu,5 Juei-Tang Cheng4,6 1Department of Nursing, Tzu Chi University of Science and Technology, Hualien City, 2Department of Pharmacy & Graduate Institute of Pharmaceutical Technology, Tajen University, Pingtung County, 3Department of Cardiology, 4Department of Medical Research

Lung cancer (LC) stands as the nike dunk high crimson tint foremost cause of cancer-related fatality rates worldwide.Early diagnosis significantly enhances patient survival rate.Nowadays, low-dose computed tomography (LDCT) is widely employed on the chest as a tool for large-scale lung cancer screening.Nonetheless, a large amount of chest radiograp